CHL 202

Laboratory for Organic Chemistry II

Spring , 2011

Text: La Salle University CHL 201-202 Laboratory Manual, Morhig, Hammond, Schatz, and Morrill, Freeman Custom Publishing, 2010 (from Modern Projects and Experiments in Organic Chemistry, Freeman, New York, 2003.)

Instructors: Thomas S. Straub, Ph.D., William A. Price, Ph.D., Laura Grande, M.S.

Date Experiment

Jan. 18 - 20 EXP 11 (19): Diels-Alder Reaction

Jan. 25 - 27 EXP 12 (20): Selectivity in the Bromination of Acetanilide - Handout

Feb. 1 - 3 EXP 13 (21): Acylation of Ferrocene

Feb. 8- 10 EXP 13 (21): continued

Feb. 15 - 17 EXP 14 (PROJECT 5.2): Grignard Synthesis of Secondary and Tertiary Alcohols

Feb. 22 – 24 EXP 14 (PROJECT 5.2): continued

March 1 - 3 EXP 16 (PROJECT 4.1): Interconversion of 4-tert-Butylcyclohexanol and 4-tert-Butylcyclohexanone. 4.1 Green Chemistry: NaOCl Oxidation

March 7 - 11 SPRING BREAK

March 15 -17 EXP 16 (PROJECT 4.2): 4.2 Sodium Borohydride Reduction

March 22 - 24 EXP 15 (18): Phase Transfer Catalysis: Synthesis of Butyl Benzoate

March 29 - 31 MICROWAVE: Fischer Esterification - Handout

April 5 - 7 EXP 17 (EXP 28.2): Synthesis of a Mosquito Repellant: N,N-Diethyl-meta-toluamide (DEET)

April 12 - 14 EXP 18 (PROJECT 11): Aldol-Dehydration Chemistry Using Unknown Aldehydes and Ketones. 11.1 Preparation and Characterization of Aldol-Dehydration Condensation Product

April 19 - 21 EXP 18 (PROJECT 11): 11.2 Preparation and Characterization of Solid Derivatives of the Unknown Aldehyde and Ketone

April 26 - 28 Check-out. All laboratory reports due!