CHEMISTRY 202
ORGANIC CHEMISTRY II
Spring Semester, 2019
Instructor: William A. Price, Ph.D.
Office: Holroyd 345
Phone: 951-1261
price@lasalle.edu
Texts:
Lecture:
L.G. Wade, Organic Chemistry, 9th Edition, Pearson, Boston, MA, 2017.
ISBN13 : 978-0-321-97137-1
Sapling Learning Homework : www.SaplingLearning.com
Sapling Learning Online Homework: $40.00 for 1 semester.
La Salle University – CHM 202 – Spring18– PRICE
Instructions for how to enroll: http://bit.ly/saplinginstructions
Laboratory:
J. R. Mohrig, C.N. Hammond, P.F. Schatz and T.C. Morrill, CHL 201-202 Laboratory Manual from Modern Projects and Experiments in Organic Chemistry, W.H. Freeman Custom Publishing, New York, 2010.
Alternatively for lab:
Mohrig, J.R., Hammond, Schatz, P.F. and Morrill, T.C., Modern Projects and
Experiments in Organic Chemistry, Freeman, New York, 2003.
Course Description and Objectives:
Chemistry 202 is a course that will build on the foundation that was established
in CHM 201. The course will begin with the study of alchohols, their synthesis and reactions. It is important to recognize that much of this continues the substitution and elimination concepts from the fall semester. We will then focus on structure elucidation using
infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy. Take a look
at some excellent tutorials and spectroscopy resources on my LINKS page. The course will then continue with the study of different functional groups in cluding ethers and epoxides, followed by conjugated pi systems including
pericyclic reactions and aromatic (benzene-type) chemistry. After a brief look
at ultraviolet (UV) spectroscopy, the course will continue with examination of structure, preparation, and
reactivity of oxygen-containing functional groups within molecules. The approach
used will incorporate orbital analysis (structure), electron distribution and
flow (mechanism), reactions, and ultimately synthesis.
The amount of material to be covered is quite large, thus it is necessary that
you keep up with the course lecture to lecture. This is most readily accomplished
by reading the appropriate chapter prior to attending class. This way, the material
covered in class will seem somewhat familiar (what a great feeling) and will
hopefully clarify any questions you might have. Do many of the chapter
problems in Wade. Do not hesitate to ask questions in class, after class
or during any office hour. Use of the study guide is helpful, but only if you
first attempt the problems on your own.
Examinations, Quizzes, Homework & Chapter Coverage:
The lecture portion of your grade will be determined by your performance on
four hourly examinations (50%), 4 take-home quizzes (10%), homework (Sapling) (5%), and the cumulative final examination (15%). The remaining 20% of the course is your laboratory grade. Hour exams will typically be given every tenth lecture with the following chapter coverage:
Exam I | Wednesday, February 6 | Chapters 10-12 |
Exam II | Friday, March 1 | Chapters 13-15 |
Exam III | Monday, April 1 |
Chapters 16-18 |
Exam IV | Friday, April 26 | Chapters 22,20 |
Quizzes (take-home) will be given midway between examinations. They will be handed out on the date listed and due the following class day at 11:45:
Quiz 1: January 25 (F); Quiz 2: February 18 (M); Quiz 3: March 20 (W), and April 10 (W)
2018-2019 La Salle Academic Calendar
Grades:
The course consists of both lecture (80%) and laboratory (20%). One cannot pass the course without passing both the lecture and the laboratory. The laboratory grade is determined solely by the laboratory instructor. Your final grade will be determined on your total number of earned points relative to those of your colleagues:
4 Hourly Exams | 500 pts | 50% |
4 Quizzes | 100 pts | 10% |
Homework | 50 pts | 5% |
Final Exam | 150pts | 15% |
Laboratory | 200 pts | 20% |
Total | 1000 pts | 100% |
Strategy:
As is evident by the ambitious examination schedule, it is important that you
keep pace with this course. It is well documented that attempting to cram three
weeks of material into a day and a half prior to an exam is an unsuccessful
method to studying in this course. Rewriting ones notes after each lecture
is an effective way to reinforce the lecture material and it typically brings
questions to the surface. Attendance will not be taken regularly, but consistent
lecture attendance is strongly urged since examinations reflect the instructors
emphasis in class.
The text contains an excellent set of problems. It is recommended that you solve the problems in the running text as you read the material (you may want to use a composition notebook for problems). Recommended problems will be suggested at the end of the chapters and can be used to fine tune your grasp of the material.
Chemistry By Design A very good website that describes syntheses of a huge number of biologically significant componds, from University of Arizona
CH 10 Alcohols - Structure and Synthesis - ppt slides
CH 11 Reactions of Alcohols - ppt slides
CH 12 Infrared Spectroscopy - ppt slides;
IR & Mass spec. powerpoint tutorial L.G. Wade
IR analysis tutor from UCLA
IR overview with problems excellent site from Michigan State, good explanations and problems
Mass Spectrometry - ppt slides
Mass spectrometry tutorial from the University of Arizona
Mass Spectrometry problem set ; Answers
IR/mass matching problems - mass spec answers
CH 13 Nuclear Magnetic Resonance Spectroscopy - ppt slides
Some spectroscopy links
Spectroscopy overview IR, UV-vis, mass and NMR with problems from MSU
NMR background, theory and essentials - from Michigan State U.
spin-spin splitting slides for both C-13 and proton NMR
Structure Elucidation Workbook very good spectral problems with IR, NMR & mass spec., Notre Dame
answers to "green" combined spectroscopy problems from Notre Dame site (see above) - available from instructor
Spectral problems 10 problems with IR, mass, proton and C-13 NMR, from Carey
NMR overview site with H-1 and combined H-1/C-13 NMR problems from Central Connecticut State
Spectroscopy problems from MSU, proton and carbon-13 NMR with IR
Combined spectroscopy problems
CH 14 Ethers: makin' em and breakin' em - ppt slides
epoxide ring-opening from chapter 14
CH 15 Conjugated Systems ppt slides
Chapter 14-15 practice problems / answers
Conjugation, MO Theory, and Pericyclic Reactions from Vanderbilt, this is a terrific overview
Introduction to M.O. Theory from Carey, a good interactive site
CH 16 Benzene & Aromaticity ppt slides
Bonding in Benzene a very good description of the Kekule description of benzene
M.O.'s of benzene, cyclobutadiene
CH 17 Chemistry of Benzene ppt slides
Chapter 16 practice problems / answers
more Chapter 16 E.A.S. rxns / answers
Nucleophilic Aromatic Substitution and Benzyne mechanistic explanations
CH 18 Ketones and Aldehydes ppt slides
Practice Problems from Chapter 18 / answers
CH 22 Alpha Substitutions and Condensations
ethyl acetoacetate and diethyl malonate rxns
alkylation via enolate and enamine
CH 19 Amines
CH 20 Carboxylic Acids
overview good summary of carboxylic acids: acidity and preparation
carboxylic acids and acid chlorides reactions
CH 21 Carboxylic Acid Deriviative
nomenclature some problems answers
hydrolysis
and Fischer esterification
CH 20-21 practice exam Q's / answers
Francis Carey's Organic Chemistry text has associated with it an excellent help site that I highly recommend. Topics are listed on the home page.
Click here to access Frank Carey's excellent site
Office Hours:
I am available Monday, Wednesday and Friday from 9:30-11:00 and at other times
by appointment. Please take advantage of these times to clarify any
lecture or laboratory material. My schedule for the semester is here
so that finding me will be easier.